Figure 2.
A schematic presentation of research approach. To understand whether synergistic effect 34 can be reproduced in vitro, we evaluated the combined effect of anti-SSEA4 and anti-Globo H antibodies by ADCC assay, and performed staining to detect the surface expression level of SSEA4 and Globo H as a reference. For surface staining, chimeric or mouse (not shown) antibodies were used. Antibody labeling for detection could be direct (not shown) or indirect. For ADCC assay, only chimeric antibodies were used.