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. Author manuscript; available in PMC: 2022 Aug 20.
Published in final edited form as: ACS Chem Biol. 2021 Aug 9;16(8):1526–1537. doi: 10.1021/acschembio.1c00396

Figure 4.

Figure 4.

ADCC induction of chimeric Ab6 and chimeric VK9 and relative expression levels of SSEA4 and Globo H on MCF-7. ADCC assay was performed as described in Methods. The results showed that chAb6 induced stronger ADCC response than chVK9 due to high SSEA4 expression. Fold of induction is calculated as described in Methods. Surface staining was performed by indirect method using 10 μg/ml unconjugated chAb6 or chVK9. The raw data are provided in Table S1.