Table 1.
Patient Characteristics
| Average age at presentation (y) | 44 |
| Average age at placement of breast implants (y) | 31 |
| Average BMI | 24 |
| Reason for implant placement | |
| Cosmetic | 226 (93%) |
| Reconstructive | 18 (7%) |
| Current smoker | 19 (8.4%) |
| Diabetes | 7 (2.8%) |
| Grade of capsular contracture | |
| I | 11 (4.7%) |
| II | 122 (52%) |
| III | 60 (25%) |
| IV | 43 (18%) |
| Autoimmune diagnosis | |
| Arthritis | 67 (27%) |
| Chronic inflammatory response syndrome (CIRS) | 3 (1.2%) |
| Lupus | 10 (3%) |
| Sjogren’s syndrome | 3 (1.2%) |
| Raynaud’s sydrome | 10 (4%) |
| Graves disease | 2 (0.8%) |
| Hashimoto’s thyroiditis | 20 (8.1%) |
| Scleroderma | 1 (0.4%) |
| Multiple sclerosis | 1 (0.4%) |
| Ulcerative colitis | 1 (0.4%) |
| Crohn’s disease | 1 (0.4%) |
| History of breast cancer | 10 (4%) |
| History of other cancer | 17 (6.9%) |
| Anxiety | 79 (32%) |
| History of panic attacks | 10 (4%) |
| Depression | 38 (15%) |
| Suicidal ideation | 1 (0.4%) |
| Fibromyalgia | 17 (6.9%) |
| Irritable bowel syndrome | 23 (9.3%) |
| Mild anemia (hemoglobin 11–11.9 g/dL) | 2 (0.8%) |
| Moderate anemia (hemoglobin 8.0–10.9 g/dL) | 2 (0.8%) |
| Leukopenia (WBC < 4.5 × 109/L) | 7 (3%) |
| Elevated alkaline phosphatase (>130 U/L) | 3 (1.2%) |