Genomic landscape of advanced breast cancer in premenopausal women. Oncoprint depicting the results of patient's ctDNA NGS data. MONALEESA-7 cfDNA at screening: Genes with frequency > 5% or genes of interest are included. BOR, best overall response; cfDNA, circulating free DNA; CR, complete response; ctDNA, circulating tumor DNA; NCRNPD, neither complete response nor progressive disease; NGS, next-generation sequencing; PBO, placebo; PD, progressive disease; PFS, progression-free survival; PR, partial response; RIB, ribociclib; SD, stable disease; SV, structural variations; UNK, unknown.