Table 2:
Cohort summary and comparison between the entire cohort of raw CPRD, HES, and ONS data the OMOP CDM cohort
| CPRD-HES-ONS source data | OMOP CDM data | |
|---|---|---|
| n | 502 723 | 502 367 |
| Median follow-up (IQR) | 9.56 (10.39) | 9.56 (10.39) |
| Demographics | ||
| Female (%) | 52.39 | 52.4 |
| Caucasian (%) | 90.81 | 90.46 |
| Most deprived fifth (%) | 15.18 | 15.18 |
| Lifestyle | ||
| Smoker (%) | 324 755 (64.59) | 331 445 (65.97) |
| Never smoker (%) | 155 995 (31.03) | 149 569 (29.77) |
| Clinical measures mean (SD) or median (IQR) | ||
| BMI (kg/m2) | 28.9 (6.44) | 28.9 (6.44) |
| SBP (mmHg) | 143.07 (22.42) | 143.07 (22.42) |
| DBP (mmHg) | 80.05 (12.19) | 80.05 (12.19) |
| Platelets | 2.39 (3.53) | 2.39 (3.53) |
| Total WBC counts | 7.49 (2.88) | 7.49 (2.88) |
| Albumin | 40.71 (4.5) | 40.71 (4.5) |
| Creatinine (µmol/L) | 102.76 (58.09) | 102.76 (58.09) |
| Hemoglobin | 129.92 (18.22) | 129.92 (18.22) |
| Medication | ||
| Loop diuretics (%) | 42.2 | 42.2 |
| ACE-I (%) | 50.2 | 50.1 |
| Βeta-blockers (%) | 48.3 | 48.2 |
BMI, body mass index; SBP, systolic blood pressure; DBP, diastolic blood pressure; WBC, white blood cell count; ACE-I, angiotensin-converting enzyme (ACE) inhibitors; IQR, interquartile range