Table 5.
Interactions Between rs769178 Polymorphisms and Risk Factors for the Risk of Allergic Rhinitis
G | E | Cases(n) | Controls | OR | 95% CI | χ2 | P | |||
---|---|---|---|---|---|---|---|---|---|---|
TT+GT/GG | Male | |||||||||
– | – | 96 | 37.2% | 162 | 62.8% | 1.00 | ||||
– | + | 205 | 47.0% | 231 | 53.0% | 1.50 | 1.09 | 2.05 | 6.350 | 0.012 |
+ | – | 89 | 53.9% | 76 | 46.1% | 1.98 | 1.33 | 2.94 | 11.447 | 0.001 |
+ | + | 210 | 61.6% | 131 | 38.4% | 2.71 | 1.94 | 3.78 | 34.920 | <0.001 |
TT+GT/GG | Overweight | |||||||||
– | – | 187 | 39.1% | 291 | 60.9% | 1.00 | ||||
– | + | 114 | 52.8% | 102 | 47.2% | 1.74 | 1.26 | 2.41 | 11.297 | 0.001 |
+ | – | 201 | 58.1% | 145 | 41.9% | 2.16 | 1.53 | 3.04 | 28.993 | <0.001 |
+ | + | 98 | 61.3% | 62 | 38.8% | 2.46 | 1.70 | 3.55 | 23.750 | <0.001 |
TT+GT/GG | Smoking | |||||||||
– | – | 210 | 41.1% | 301 | 58.9% | 1.00 | ||||
– | + | 91 | 49.7% | 92 | 50.3% | 1.42 | 1.01 | 1.99 | 4.087 | 0.043 |
+ | – | 215 | 57.3% | 160 | 42.7% | 1.93 | 1.35 | 2.75 | 22.847 | <0.001 |
+ | + | 84 | 64.1% | 47 | 35.9% | 2.56 | 1.72 | 3.81 | 22.271 | <0.001 |
TT+GT/GG | Family history | |||||||||
– | – | 192 | 38.1% | 312 | 61.9% | 1.00 | ||||
– | + | 109 | 57.4% | 81 | 42.6% | 2.19 | 1.558 | 3.069 | 20.869 | <0.001 |
+ | – | 194 | 55.1% | 158 | 44.9% | 2.00 | 1.398 | 2.849 | 24.244 | <0.001 |
+ | + | 105 | 68.2% | 49 | 31.8% | 3.48 | 2.372 | 5.111 | 43.118 | <0.001 |
TT+GT/GG | Asthma | |||||||||
– | – | 197 | 34.4% | 375 | 65.6% | 1.00 | ||||
– | + | 104 | 85.2% | 18 | 14.8% | 11.00 | 6.48 | 18.67 | 105.676 | <0.001 |
+ | – | 183 | 47.9% | 199 | 52.1% | 1.75 | 1.34 | 2.28 | 17.328 | <0.001 |
+ | + | 116 | 93.5% | 8 | 6.5% | 27.60 | 13.21 | 57.67 | 143.871 | <0.001 |