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. Author manuscript; available in PMC: 2021 Sep 7.
Published in final edited form as: ACS Nano. 2020 Oct 29;14(11):14528–14548. doi: 10.1021/acsnano.0c07581

Figure 3. Nanoparticle enhanced SPR platforms.

Figure 3.

a Dual Au nanoparticle-assisted signal amplification for exosome detection. b SPR spectra of (1) aptamer modified Au film; (2) target exosomes; (3) reaction with T30 AuNPs; (4) reaction with A30 AuNPs; (5) regeneration. c SPR response of dual AuNP-assisted SPR sensor. d The relationship between Δθ and exosomes concentrations by using different sensing strategies: direct measurement, single AuNP amplified SPR aptasensor, and dual AuNP amplified SPR aptasensor. e Reproducibility investigation of the SPR biosensor. Reprinted with permission from ref. 27. Copyright 2019 Elsevier.