Table 1.
Hierarchical clustering analyses.
| Raw | Adjusted | ||||
|---|---|---|---|---|---|
| HR (95% CI) | P value | HR (95% CI) | P value | ||
| TCGA data | |||||
| Clustered RS (RT/NRT) | 0.346 (0.210–0.570) | <0.001 | 0.253 (0.147–0.438) | <0.001 | |
| Clustered RR (RT/NRT) | 1.143 (0.612–2.135) | 0.676 | 1.411 (0.682–2.918) | 0.353 | |
| RT patients (RS/RR) | 0.436 (0.250–0.762) | 0.004 | 0.437 (0.242–0.788) | 0.006 | |
|
| |||||
| METABRIC data | |||||
| Clustered RS (RT/NRT) | 0.734 (0.567–0.950) | 0.019 | 0.650 (0.491–0.862) | 0.003 | |
| Clustered RR (RT/NRT) | 0.882 (0.767–1.014) | 0.078 | 0.868 (0.751–1.004) | 0.056 | |
| RT patients (RS/RR) | 0.687 (0.565–0.835) | <0.001 | 0.741 (0.606–0.907) | 0.004 | |
The adjusted factors included age, pathological stage (grade), histological type, ER, PR, HER, and chemotherapy. HR, hazard ratio; 95% CI, 95% confidence interval; RT, radiotherapy; NRT, nonradiotherapy; RS, radiosensitive; RR, radioresistant.