Table 1.

Sample Demographics

	HD Gene Positive, n = 35	HD Gene Negative, n = 35	p Value
Age, Years	29.4 (5.7)	30.5 (5.2)	.41a
Sex, Female, n	19	20	.81b
Handedness, Right, n	30	32	.70b
NART	102.2 (6.9)	103.4 (8.3)	.52a
Depressive Score	32.2 (8.6)	34.6 (7.4)	.22a
Adjusted Caudate Volume, mL	7.27 (0.75)	7.42 (0.67)	.40a
UHDRS Motor Score, Median (Maximum)	0 (5)
CAG Repeat Length	41.8 (1.2)
Disease Burden Score	185.1 (33.5)

Values are reported as mean (SD) unless otherwise stated.

Sample demographics for both groups show that the cohorts were well matched at recruitment for age, sex, and handedness. Groups were matched for intelligence, as measured by the NART, and for depressive symptoms, as measured on the Zung Depressive Scale. Groups were in the normal range for depressive symptoms (<50). Caudate volumes adjusted for total intracranial volume (see Methods and Materials) were also not significantly different between groups.

HD, Huntington's disease; NART, National Adult Reading Test; UHDRS, Unified Huntington's Disease Rating Scale.

^aThe p value was calculated via independent t test.

^bThe p value was calculated via χ² test.