Table 2.
Replication Analysis at Cue Presentation Across HD Gene–Positive and HD Gene–Negative Groups
| Gain > Neutral Cue |
Loss > Neutral Cue |
Q Value |
||||
|---|---|---|---|---|---|---|
| t | p | t | p | t | p | |
| Left VS | 3.61 | <.001 | 4.76 | <.001 | −0.018 | .5 |
| Right VS | 5.77 | <.001 | 6.77 | <.001 | −0.014 | .51 |
| Medial PFC | 2.75 | <.004 | −1.71 | .95 | 5.61 | <.001 |
| Bilateral Insula | 1.22 | .11 | 6.33 | <.001 | Not tested | Not tested |
N = 70.
The table describes the 1-sided t statistic and corresponding p value whether activity in regions of interest, defined from existing literature, was positively associated with contrast at cue presentation.
HD, Huntington's disease; PFC, prefrontal cortex; VS, ventral striatum.