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. 2021 Aug 5;37(9):2787–2797. doi: 10.1007/s00381-021-05244-2

Table 2.

Results of neurological and functional testing according to histology and affected lesion location

PA
(n = 13)
MB
(n = 18)
DN +
(n = 15)
DN −
(n = 16)
SCP +
(n = 16)
SCP −
(n = 15)
SCP + or DN +
(n = 21)
SCP − and DN −
(n = 10)
Ataxia ICARS total score 4 (3)* 9 (13.5)* 11 (16) 6 (5.3) 13.5 (5.3)** 4 (3)** 9.0 (14) 4.0 (3.3)
ICARS mean z-score 1.4** 9.7** 13.8 5.8 17.2** 2.4** 9.8 3.2
Fine motor hand function Drawing
F −0.72** −1.61** −1.36 −1.10 −1.9 −0.8 −1.3 −1.5
NCV 0.72** 2.52** 1.89 1.61 2.8* 1.1* 1.7 1.5
Writing sentence
F −0.6 −1.05 −1.41* −0.35* −1.1* −0.3* −1.0* −0.1*
NCV 0.34 1.22 1.54* 0.22* 1.0** −0.2** 0.8* −0.2*
Intelligence FSIQ 102 (21) 88 (22.5) 88 (14) 102 (24) 87.5 (33)* 102 (25)* 88 (23.5)* 103.5 (16.8)*
VIQ 100 (19) 93 (14.3) 89 (25) 100 (18) 89 (27) 100 (20) 89 (21.5)* 102 (13.3)*
PIQ 94 (27) 86.5 (18.5) 84 (9)* 101 (26.3)* 83 (15.8)* 97 (27)* 84 (13)** 105.5 (19.5)**
Planning ToL
acPRS 24 (56) 38.5 (51.3) 24 (81) 49.5 (51.3) 28.5 (63) 53 (67) 24 (64.5) 63 (44)
Executive function Baseline speed −1.16** −0.03** −0.47 −0.89 0.0** −1.0** −0.4 −0.9
Feature identification
Dissimilar −0.77 −0.11 0.06 −0.46 0.2 −0.7 −0.2 −0.5
Similar 0.80** 0.92** 0.16 −0.07 0.2 −0.2 0.1 −0.2
Shifting attention
Compatible fixed −0.27** 1.84** 1.05 0.48 1.6* 0.2* 1.1 0.3
Incompatible fixed 1.05 0.90 1.48 0.71 1.1 0.6 1.3 0.5
Compatible random 0.63 1.34 1.02 0.97 1.4 0.9 1.3 0.4
Incompatible random 0.28* 1.28* 0.90 0.59 1.3* 0.3* 1.2 0.2

Median values and interquartile ranges (IQR)

PA pilocytic astrocytoma, MB medulloblastoma, DN + lesion in dentate nucleus DN − no lesion in dentate nucleus, SCP + lesion in superior cerebellar peduncle, SCP − no lesion in superior cerebellar peduncle, F frequency, NCV automation of fine motor hand function, FSIQ full scale intelligence quotient, VIQ verbal IQ, PIQ performance IQ, ToL Tower of London, acPRS age-corrected percentile rank score

*p < 0.05, **p < 0.01