Table 1.
Entire UPS cohort | Discovery cohort | Expansion cohort | |
---|---|---|---|
N = 15 | N = 10 | N = 5 | |
Follow-up months (range, SD) | 20.2 (4–46, 12) | 20.5 (4–46; 12.1) | 19.6 (12–43; 13.1) |
Lost to follow-up | 0 | 0 | 0 |
Female | 6 (40%) | 4 (40%) | 2 (40%) |
Age (range, SD) | 69.5 (48–85; 9.6) | 69.3 (48–85;11.3) | 70 (62–76; 6) |
Stage | |||
II | 4 (26.7%) | 3 (30%) | 1 (20%) |
III | 8 (53.3%) | 4 (40%) | 4 (80%) |
IV | 3 (20%) | 3 (30%) | |
Tumor size cm (range, SD) |
9.8 (3–34; 8.1) | 8.8 (3–21.5, 5.6) | 11.7 (3–34; 12.5) |
Deep | 10 (66.7%) | 6 (60%) | 4 (80%) |
Grade 3 | 14 (93.3%) | 9 (90%) | 5 (100%) |
Received neoadjuvant chemotherapy | 1 (6.7%) | 1 (10%) | 0 (0%) |
Received neoadjuvant radiation | 1 (6.7%) | 1 (10%) | 0 (0%) |
Adjuvant radiation | 13 (86.7%) | 9 (90%) | 4 (80%) |
(IORT or EBRT) | |||
Local recurrence | 1 (6.7%) | 0 | 1 (20%) |
Metastatic recurrence | 3 (20%) | 2 (20%) | 1 (20%) |
Current status | |||
NED | 10 (66.7%) | 8 (80%) | 2 (40%) |
AWD | 2 (13.3%) | 0 | 2 (40%) |
DOD | 2 (13.3%) | 2 (20%) | 0 |
DWD | 1 (6.7%) | 0 | 1 (20%) |