Table 1.
Comparison of demographic and clinical characteristics of COVID-19 patients with and without Cystic Fibrosis before and after propensity score matching.
|
Variable |
Before matching |
After matching |
||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Cystic Fibrosis cohort (n = 422) |
Non-CF cohort (n = 507,388) |
Std Diff | Cystic Fibrosis cohort (n = 413) |
Non-CF cohort (n = 413) |
Std Diff | |||||
| Number | Percent/SD | Number | Percent/SD | Number | Percent/SD | Number | Percent/SD | |||
| Demographics | ||||||||||
| Age (Mean) | 46.6 | 19.3 | 46.7 | 19.1 | <0.01 | 47.0 | 19.3 | 47.5 | 19.3 | 0.01 |
| Male | 197 | 46.68 | 223,703 | 44.09 | 0.05 | 191 | 46.25 | 187 | 45.28 | 0.02 |
| Female | 225 | 53.32 | 281,108 | 55.40 | 0.04 | 222 | 53.75 | 226 | 55.42 | 0.02 |
| BMI (30 and above) | 113 | 26.78 | 107,267 | 21.14 | 0.13 | 113 | 27.36 | 130 | 31.48 | 0.09 |
| African American | 58 | 13.74 | 86,406 | 17.03 | 0.09 | 58 | 14.04 | 62 | 15.01 | 0.03 |
| Caucasian | 309 | 73.22 | 310,774 | 61.25 | 0.26 | 301 | 72.88 | 298 | 72.16 | 0.02 |
| Hispanic or Latino | 47 | 11.34 | 65,000 | 12.81 | 0.05 | 47 | 11.38 | 44 | 10.65 | 0.02 |
| Comorbidities | ||||||||||
| Hypertension | 203 | 48.10 | 146,339 | 28.84 | 0.40 | 197 | 47.7 | 211 | 51.09 | 0.08 |
| Chronic kidney disease | 91 | 21.56 | 31,005 | 6.11 | 0.46 | 87 | 21.07 | 63 | 15.25 | 0.15 |
| Chronic lower respiratory diseases | 259 | 61.37 | 84,682 | 16.69 | 1.03 | 250 | 60.52 | 251′ | 60.78 | 0.01 |
| Diabetes mellitus | 197 | 46.68 | 73,411 | 14.47 | 0.75 | 188 | 45.52 | 198 | 47.94 | 0.05 |
| Ischemic heart disease | 95 | 22.51 | 44,337 | 8.74 | 0.39 | 92 | 22.8 | 93 | 22.52 | 0.01 |
| Nicotine dependence | 52 | 12.32 | 39,685 | 7.82 | 0.15 | 52 | 12.59 | 40 | 9.69 | 0.09 |
Abbreviation: CF: Cystic Fibrosis, SD: Standard Deviation, Std Diff: Standard Difference.