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. 2021 Sep 7;4:1046. doi: 10.1038/s42003-021-02587-z

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© The Author(s) 2021

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 5 — a The impacts of methimazole on intestinal microbial alpha diversity, the points in the same color represented the different subjects in the same time points. b Principal coordinates analysis (PCoA) based on Bray-Curtis distances of metagenomic species, the points in the same color represented the same subjects in the different time points. c The significantly different metagenomic species among different time points. d Dynamic in the relative abundance of function genes including antibiotic resistance gene and mobile genetic elements.