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. 2021 Sep 8;6(5):100274. doi: 10.1016/j.esmoop.2021.100274

Figure 4.

Figure 4

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) neutralizing antibody response generated after BNT162b2 vaccine administration.

Virus neutralizing test with neutralizing titer 50% neutralization titers (NT50) defined as the sample dilution (reciprocal titer) conveying 50% neutralization in SARS-CoV-2 (strain 2019-nCoV-Italy-INMI1, reference 008V-03893, passage 5) infected wells. (A) In vitro SARS-CoV-2 NT50 toward the wild-type Wuhan strain 28 days after the booster dose in the different study groups. (B) Correlation between SARS-CoV-2 anti-RBD immunoglobulin G (IgG) and NT50 with regression line for all values above the lower limit of quantification (LLQ). Geometric mean titers (GMTs) of the NT50 are presented, with the dotted line indicating LLQ. Values below the LLQ are imputed to 1/10 LLQ for NT50. I bars indicate standard errors.