Table 2.
The list of differently expressed synaptosomal proteins between Control + Tian versus Control and CSIS + Tian versus CSIS.
| Protein name | UniProtKB accession no | Gene | Fold change | Fold change |
|---|---|---|---|---|
| Control + Tian versus Control | CSIS + Tian versus CSIS | |||
| Phosphoglycerate mutase 1 | P25113 | Pgam1 | 3.99 | 2.14 |
| 14–3-3 protein zeta/delta | A0A0G2JV65 | Ywhaz | 3.41 | 2.06 |
| Ras-related protein Rab-3A | P63012 | Rab3a | 2.52 | 1.41 |
| Rat lipophilin | Q63436 | N/A | 2.04 | 1.22 |
| RAB33B, member RAS oncogene family | F1LW77 | Rab33b | 2.01 | 1.76 |
| Glyceraldehyde-3-phosphate dehydrogenase | D3ZGY4 | N/A | 4.52 | 0.76 |
| Alpha-1,4 glucan phosphorylase | G3V6Y6 | Pygb | 3.91 | 0.76 |
| Beta-enolase | P15429 | Eno3 | 3.71 | 0.71 |
| Dynamin-1 | P21575 | Dnm1 | 3.18 | 0.63 |
| Clathrin heavy chain | F1M779 | Cltc | 3.01 | 0.51 |
| Spectrin alpha chain, non-erythrocytic 1 | A0A0G2K1Y8 | Sptan1 | 2.58 | 0.73 |
| Tubulin alpha chain | A0A0H2UHM7 | LOC100909441 | 2.52 | 0.59 |
| Spectrin beta chain | G3V6S0 | Sptbn1 | 2.50 | 0.75 |
| Contactin-1 | Q63198 | Cntn1 | 2.46 | 0.75 |
| Tenascin-R | F1LQ63 | Tnr | 2.46 | 0.58 |
| Vesicle-fusing ATPase | A0A0G2K6U1 | Nsf | 2.44 | 0.64 |
| Fructose-bisphosphate aldolase | A0A0G2K3Q6 | Aldoc | 2.40 | 0.68 |
| Beta-actin | A0A068F1Y2 | Actb | 2.33 | 0.80 |
| ATPase H + -transporting V1 subunit A | A0A1W2Q6N0 | Atp6v1a | 2.28 | 0.65 |
| Dephosphin long form | Q7M077 | N/A | 2.20 | 0.23 |
| Neurofascin | D3ZW56 | Nfasc | 2.16 | 0.71 |
| Aspartate aminotransferase, cytoplasmic | P13221 | Got1 | 2.15 | 0.78 |
| Syntaxin-binding protein 1 | P61765 | Stxbp1 | 2.09 | 0.77 |
| Septin 5 | D3ZT07 | Sept5 | 2.04 | 0.79 |
| Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | P63329 | Ppp3ca | 2.03 | 0.69 |
| Tubulin alpha-4A chain | Q5XIF6 | Tuba4a | 2.00 | 0.56 |
| Mitogen-activated protein kinase 1 | P63086 | Mapk1 | 2.00 | 0.74 |
| Protein kinase C and casein kinase substrate in neurons protein 1 | A0A0G2JWR2 | Pacsin1 | 1.84 | 0.74 |
| Phosphoglycerate kinase | M0R6Y8 | RGD1560402 | 1.66 | 0.71 |
| ATPase, H + transporting, V1 subunit E isoform 1, isoform CRA_a | G3V7L8 | Atp6v1e1 | 1.28 | 0.66 |
| Guanine deaminase | Q9JKB7 | Gda | 1.24 | 0.75 |
CSIS-chronic social isolation, Tian-tianeptine. Proteins were identified according to MS/MS spectra search against the Uniprot/Swissprot database using the Proteome Discoverer (version 1.3) search engine (Thermo Fisher Scientific).