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. 2021 Aug 25;8:727053. doi: 10.3389/fmolb.2021.727053

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Copyright © 2021 Fernando, Dickwella Widanage, Penfield, Lipton, Washton, Latgé, Wang, Zhang and Wang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Comparison of chitin forms identified in different fungal species. (A) Chemical shift RMSD heatmap comparing the chitin forms observed in different fungi. Good correlations with RMSD of less than 0.5 ppm are highlighted using crosses. (B) Linear discriminant analysis with Candida fungi (C. albicans and C. auris) classified differently from other fungal species, with linear discriminant 1 (LD1) scores shown in a histogram. This panel mainly shows the frequency in which LD1 scores fall into a particular range (the width of each bar). (C) Gaussian probability distributions of LD1 scores. The Candida data falls into a smaller range than the other fungi, therefore, there is a much higher probability that a Candida species will fall near their statistical mean. (D) LD1 loadings corresponding to the chemical shifts of each carbon site.