Table 2.

MRI-based coordinates of the viral injection paths for each monkey.

Monkey	Coordinates of bilateral SNs for viral injections
	AAV9-SaCas9-SgPINK1+DJ-1 side				AAV9-SaCas9-SgControl side
Middle age 1: 070229	Path	Path 1: −6.80	Path 3: −4.80	Path 5: −2.80	Path 2: −6.80	Path 4: −4.80	Path 6: −2.80
	s	+27.20	+27.20	+27.20	−24.60	−24.60	−24.60
	d	−36.70	−36.70	−36.70	−34.50	−34.50	−34.50
	θ	37°	37°	37°	35°	35°	35°
Middle age 2: 070209	Path	Path 1: −6.40	Path 3: −4.40	Path 5: −2.40	Path 2: −6.40	Path 4: −4.40	Path 6: −2.40
	s	−26.00	−26.00	−26.00	+25.70	+25.70	+25.70
	d	−35.00	−35.00	−35.00	−36.00	−36.00	−36.00
	θ	41°	41°	41°	38°	38°	38°
Old 1: 94089	Path	Path 1: −6.35	Path 3: −4.35	Path 5: −2.35	Path 2: −6.35	Path 4: −4.35	Path 6: −2.35
	s	+24.70	+24.70	+24.70	−24.80	−24.80	−24.80
	d	−36.80	−36.80	−36.80	−37.00	−37.00	−37.00
	θ	37°	37°	37°	37°	37°	37°
Old 2: 97093	Path	Path 1: −2.00	Path 3: 0	Path 5: 2.00	Path 2: −2.00	Path 4: 0	Path 6: 2.00
	s	−23.90	−23.90	−23.90	+25.20	+25.20	+25.20
	d	−38.10	−38.10	−38.10	−38.00	−38.00	−38.00
	θ	35°	35°	35°	37°	37°	37°

Coordinate description: Path: anterior (−) or posterior (+) to the plane with the markers (mm), s: left (+) or right (−) of the midsagittal plane (mm), d: distance (−) from the skull surface  to the most medial SN (mm), θ: angle between the injection path and the axis of symmetry of brain (°).