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. 2021 Aug 25;8:726753. doi: 10.3389/fmed.2021.726753

Table 3.

Characteristics of oral manifestations reported in case reports and case series.

References (location) Cases Sex/age (years) Oral manifestations General findings
Afsal et al. (55) (India) 3 cases NA Inflammation of the papillae of Wharton's Duct; hyposalivation Mild fever, myalgia, throat pain
Aghazadeh et al. (56) (Iran) 1 case F/9 Herpetiform eruption comprising vesicles and erosions on the lips, anterior tongue, and buccal mucosa High fever, severe weakness, loss of appetite, abdominal pain, diarrhea; dry cough, shortness of breath, tachypnea, hypoxia; deep red, edematous papules and plaques on the dorsal aspect of hands and feet
Al-Khanati et al. (57) (Syria) 1 case M/24 Two aphthous-like ulcers on the lower lip with pain; areas of overgrowth and absence of filiform papillae in the tongue with burning sensation; inflammatory and purulent areas on the pharyngeal wall Very severe pain all over the body, especially in the shoulders, lower back, and knees; very severe headache, dizziness, loss of appetite, nausea, high temperature
Amorim Dos Santos et al. (58) (Brazil) 1 case M/67 Persistent white plaque and multiple pinpoint yellowish ulcers- similar to herpetic recurrent oral lesions- on the dorsal part of the tongue; a 1 cm nodule on the lower lip suggestive of fibroma; extremely viscous saliva; plaque resolved with treatment and was replaced by an asymptomatic geographical tongue Respiratory symptoms, progressive dyspnea on exertion, fever, diarrhea, hypogeusia