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. 2021 Aug 25;8:726753. doi: 10.3389/fmed.2021.726753

Table 4.

Grades of evidence (GRADE tool).

Outcome Result Number of participants (studies) Certainty of the evidence (GRADE) References
Oral lesions in general 0.33 (95% CI 0.11–0.60) 1,313 (3) ⊕⊕⊖⊖ Low (18, 22, 25)
Xerostomia 0.48 (95% CI 0.45–0.51) 946 (4) ⊕⊕⊕⊖ Moderate (18, 19, 21, 23)
Aphthous lesions 0.10 (95% CI= 0.01–0.24) 2,187 (4) ⊕⊕⊖⊖ Low (19, 22, 25, 27)