Table 5.
Diagnostic performance indexes
| Sensitivity (%) | Specificity (%) | AUC | P | Youden index | |
|---|---|---|---|---|---|
| LGCK-7 | 82.1 | 76.0 | 0.837 | *** | 0.581 |
| LGCK-19 | 75.0 | 91.9 | 0.905 | *** | 0.669 |
| LGGrade | 65.2 | 93.3 | 0.800 | *** | 0.585 |
| LGGPC-3 | 57.5 | 92.3 | 0.760 | ** | 0.498 |
Note: (1) Both ** and *** suggest that there is a significant difference between the AUC of diagnostic model and AUC of 0.500.
**
indicates P < 0.01,
***
indicates P < 0.001.
(2) LGCK-7, LGCK-19, LGGrade and LGGPC-3 are the abbreviations of logistic regression-based model for achieving diagnosing patients with different histopathological characteristics. AUCs, areas under the curve; LGCK-7, positive cytokeratin 7; LGCK-19, positive cytokeratin 19; LGGPC-3, positive Glypican-3; LGGrade, high grade hepatocellular carcinoma.