Table 3.
Results of subgroup analysis using ROX index for predicting HNFC failure.
| Categories | Sensitivity (95% CI) | Specificity (95% CI) | sAUC (95% CI) | DOR (95% CI) | I2 |
|---|---|---|---|---|---|
| Time from onset to ROX- index assessment | |||||
| All studies | 0.70 (0.59 – 0.80) | 0.79 (0.67 – 0.88) | 0.81 (0.77 – 0.84) | 9 (5 – 16) | Sensitivity: 86.05% Specificity: 85.03% |
| Within 6 h | 76 (0.65 – 0.84) | 0.74 (0.62 – 0.83) | 0.81 (0.78 – 0.84) | 9 (5 –15) | Sensitivity: 77.15% Specificity: 75.79% |
| Cut-off value | |||||
| Cut-off ≤5 | 0.65 (0.48 – 0.79) | 0.75 (0.59 – 0.87) | 0.76 (0.72 – 0.80) | 6 (4 – 9) | Sensitivity: 77.01% Specificity: 84.38% |
| Cut-off >5 | 0.77 (0.65 – 0.86) | 0.85 (0.67 – 0.94) | 0.87 (0.83 – 0.89) | 19 (11 – 35) | Sensitivity: 76.53 Specificity: 89.15% |
sAUC – summary area under the curve, DOR- diagnostic odds ratio, CI- confidence interval.