Table 4.
Authors | Target genes | LOD (copy/reaction) | Sensitivity and specificity | TAT (min) |
---|---|---|---|---|
Lu et al.46 | N, S and RdRp | 118.6 | 94 and 90% | 20 |
Huang et al.47 | N, S and RdRp | 20 | 100 and 100% | 30 |
Yan et al.48 | ORF1a/b | 20 | 100 and 100% | 60 |
Baek et al.49 | N | 100 | 100 and 98.70% | 30 |
Lu et al.50 | RdRp | 30 | 100%/– | 40 |
Jiang et al.51 | ORF1b and N | 500 copies/mL | 91.4 and 99.5% | 30 |
Kitawaya et al.52 | N and S | 10 copies/μL | 100 and 97.6% | 35 |
LOD limit of detection, N nucleocapsid protein, ORF open reading frame, RdRp RNA-dependent RNA polymerase, S spike protein, TAT turn-around time.