Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

letter

. 2021 Sep 8;11:171. doi: 10.1186/s13578-021-00684-4

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

PMC Copyright notice

Fig. 2 — Inferring SARS-CoV-2 functional genomics. A The functional landscape of the SARS-CoV-2 genome based on Metascape. Each node represents a functional term from the KEGG Pathway, GO Biological Processes, and Reactome Gene Sets. B Illustration showing SARS-CoV-2 entry into the host cell via the S protein-mediated cell membrane fusion process. The SARS-CoV-2 structure is from “Mol*” (https://molstar.org/). The full 3D view of protein structure is

available at PDB database (https://www.rcsb.org/). C Barplot showing mRNA and protein expression levels of ACE2 and NRP1 in human organs or systems. The mean expression level of each organ/system is marked with a dashed line. D Heatmap showing the mRNA and protein expression abundance of viral S gene-related reproductive SR genes in the human reproductive system