. 2021 Jan 24;11(8):2243–2264. doi: 10.1016/j.apsb.2021.01.012

Table 3.

Monocarboxylate-H⁺ co-transporters (MCTs) in cancer.

Cancer	MCT1	MCT2	MCT3	MCT4	MCT5	MCT6	MCT8	MCT9	MCT10	MCT11	MCT12	MCT13	MCT14
Adrenal gland	1.27	29.11	1.27	2.53	29.11	3.8	2.53	1.27	2.53	10.13	3.8	8.86	20.25
Breast	6.79	2.9	1.36	8.33	2.99	5.53	7.7	2.54	4.35	3.35	2.36	7.34	4.62
CNS	4.45	3.59	5.02	4.88	5.6	4.45	5.02	3.16	2.58	4.43	2.15	4.02	3.16
Cervix	4.89	1.63	2.93	5.54	2.28	3.58	8.47	10.42	3.58	2.61	3.91	3.58	1.63
Endometrium	5.15	3.16	5.65	4.32	6.31	4.49	6.31	8.64^a	9.47	5.15	4.98	7.14	6.64
Hematop. & Lymph.	2.26	5.43	2.26	4.52	11.31	4.07	5.43	21.72	4.52	4.98	4.52	3.17	3.17
Kidney	6.37	3	2.17	5.17	3.75	3.67	3.83	3.64	3.67	14.5	6	13.33	4.67
Large intestine	2.79	3.93	3.11	4.26	6.39	8.69	6.56	4.43	3.93	3.11	5.25	1.15	3.11
Liver	4.02	3.49	3.22	6.43	6.43	6.43	8.04	2.14	3.22	3.49	6.97	0.8	2.41
Lung	4.91	3.73	5.4	6.87	2.75	5.5	2.45	4.22	2.85	1.08	2.65	11.19	8.15
Oesophagus	6.4	5.6	9.6	0.8	0.8	9.6	12	3.2	5.6	1.6	11.2	10.4	10.4
Ovary	18.05	2.26	3.01	12.03	6.77	22.18	6.39	6.39	6.77	1.88	12.41	28.95^b	4.14
Pancreas	2.76	3.35	9.5	5.59	6.15	6.15	2.79	10.06	2.79	9.5	7.82	11.17	6.15
Prostate	3.41	5.02	0.4	4.82	2.41	3.61	n/a	5.22	5.62	4.82	4.42	1.2	5.22
Skin	6.34	4.65	1.9	5.5	2.96	5.29	2.75	2.75	2.33	7.61	1.48	5.29	0.85
Soft tissue	3.42	1.9	0.76	4.94	1.52	4.18	5.7	4.36	9.89	2.66	2.28	4.94	9.13
Stomach	6.32	10.18	8.42	7.02	7.37	6.67	4.21	8.07	8.07	14.39	4.21	11.23	4.91
Thyroid	3.12	3.51	1.95	4.29	3.12	4.29	6.04	3.9	5.85	3.31	4.29	4.09	4.29
Upper aerodig. tract	5.36	3.26	2.49	4.79	1.15	6.7	10.15	4.02	4.6	3.26	2.68	7.09	6.13
Urinary tract	9.59	4.17	1.96	6.62	5.64	7.6	2.21	7.35	1.72	3.19	0.49	7.35	3.43

Overexpression levels of the monocarboxylate-H⁺ co-transporter (MCT) family members in cancer affecting several tissues.

Asterisks: also downregulated in some patients.

Overexpression >20% in bold letters.

n/a, not available.

(5%–10%).

(10%–15%).