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. 2021 Mar 13;11(8):2362–2395. doi: 10.1016/j.apsb.2021.03.019

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© 2021 Chinese Pharmaceutical Association and Institute of Materia Medica, Chinese Academy of Medical Sciences. Production and hosting by Elsevier B.V.

This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).

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Applications of MOFs in diabetes therapy (A) glucose-responsive insulin release from the MOF-based nanosystem. Reprinted with permission from Ref. 215. Copyright © 2018, The Royal Society of Chemistry (B) Microneedles containing Co-ZIF-8 embodied insulin and GOx for transdermal insulin delivery. Reprinted with permission from Ref. 216. Copyright © 2020, American Chemical Society (C) FA modified Cu-MOFs (F-HKUST-1) for the therapy of chronic nonhealing wounds. Reprinted with permission from Ref. 97. Copyright © 2018, American Chemical Society.