Table 2.
Classification of MOFs by organic linkers.
| Family of linkers | Organic linker | Drug loading | Ref. |
|---|---|---|---|
| Carboxylate ligands | 1,3,5-Benzenetricarboxylate acid | Doxorubicin | 69 |
| 4,4ʹ,4ʹʹ-Benzene-1,3,5-triyl-tribenzoate | Ibuprofen | 82 | |
| 5,5ʹ,5ʹʹ-(1,3,5-Triazine-2,4,6-triyl) tris(azanediyl)triisophthalate | 5-Fluorouracil | 75 | |
| Biphenyl-4,4ʹ-dicarboxylic acid | Hydrochloride | 76 | |
| Azobenzene-4,4ʹ-dicarboxylic acid | Etilefrine | 76 | |
| Pyrazolate ligands | Bis (pyrazolate) ligand (1,4-bis(1H-pyrazol-4-yl)-2-X-benzene (H2BDP_X; X = H, NO2, NH2, OH) | Mitoxantrone | 74 |
| Imidazolate | 2-Methylimidazolate | 5-Fluorouracil | 77 |
| Polysaccharide | Cyclodextrin | Lansoprazole | 67 |
| Other polysaccharides (agar, dextran) | Procainamide | 43 | |
| BioMOFs | Nicotinic acid | Vitamin B3 | 107 |
| Succinic acid | Cisplatin | 109 | |
| Fumarate ligands | Doxorubicin | 57 |