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Chemical structure of pirfenidone (PFD), fumaric acid (FA) and trimesic acid (TA); hydrogen bonding between the PED‒FA cocrystal and PFD‒TA cocrystal; solubility results of the PFD, PFD‒FA and PFD‒TA cocrystals. Adapted from the Ref. 175 with the permission. Copyright © 2019 American Chemical Society.
