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. 2021 Mar 23;11(8):2537–2564. doi: 10.1016/j.apsb.2021.03.030

Figure 25.

Figure 25

(A) Chemical structures of sulfamethazine (STH) and p-aminobenzoic acid (PABA). (B) Antibacterial effect of STH, PABA, physical mixture and STH‒PABA cocrystal on E. coli. Different letters within the figure denote a significant difference (P < 0.05). (C) Transmission Electron Microscopy (TEM) images of E. coli before (a) and after treatment with 500 μg/mL STH (b), PABA (c), and cocrystals (d) for 12 h. Adapted from the Ref. 184 with the permission. Copyright © 2019 American Chemical Society.