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Isothermal ternary phase diagram of a cocrystal: (a) similar solubilities of the API and coformer in solvent; (b) different solubilities of the API and coformer in solvent; 1: A and solvent; 2: A and cocrystal; 3: cocrystal; 4: mixture of B and cocrystal; 5: B and solvent and 6: solution. Adapted from the Ref. 32 with the permission. Copyright © 2008 Royal Society of Chemistry.
