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. 2021 Sep 7;9(1):e002299. doi: 10.1136/bmjdrc-2021-002299

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© Author(s) (or their employer(s)) 2021. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/.

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Cox proportional hazards model estimating the HR of each variable while accounting for all other variables. The statistically significant HRs are in boldface. Here, longitudinal HbA1c, which is stratified by adequate and poor glycemic control, is shown to be the largest risk factor for COVID-19-related severity. When longitudinal HbA1c is categorized per 1% difference, its HR is 1.12 (95% CI 1.09 to 1.15, p<0.001). ACEi, ACE inhibitor; ARB, angiotensin receptor blocker.