Table 1. Cell lines used in the study.
Cell line | Origin | Mutation | Characteristics |
---|---|---|---|
SK-MEL-28 | Human | BRAFV600E; TP53 | Proliferative |
MM011 | Human | NRASQ61 | Proliferative |
MM034 | Human | BRAFV600E | Proliferative |
MM099 | Human | BRAFV600E | Invasive |
MM165 | Human | NRASQ61 | Invasive |
MM383 | Human | BRAFV600E | NCSC |
WM852 | Human | NRASQ61 | NCSC |
IGR37 | Human | BRAFV600E | Immunotherapy resistant |
YUMM 1.7 | Mouse | BRAFV600E; PTEN−/−; CDKN2−/− | Immunotherapy resistant |
YUMMER 1.7 | Mouse | BRAFV600E; PTEN−/−; CDKN2−/− | Immunotherapy sensitive |
UM 92.1 | Human | GNAQQ209L | Uveal melanoma |
Mutational and phenotypic status of cell lines used.