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Biodistribution of orally administered AuNP and Lf-PEG-AuNP. Gold accumulation of organs after 24 h of administration of AuNP and Lf-PEG-AuNP that measured by ICP-MS. Data were expressed as means ± SEM (n = 4).
| Kidney | Spleen | Heart | Lung | Liver | |
|---|---|---|---|---|---|
| AuNP [Au] (ppb = μg/kg) | 64.0 ± 31.0 | 85.3 ± 54.9 | 61.9 ± 47.3 | 49.4 ± 46.1 | 22.5 ± 11.7 |
| Lf-PEG-AuNP [Au] (ppb = μg/kg) | 65.8 ± 35.2 | 66.9 ± 22.8 | 185.9 ± 88.7a) | 108.7 ± 76.6a) | 22.0 ± 14.1 |
P < 0.01 versus AuNP itself group.
