Average heart rate (A), PR interval (B), QRS duration (C), QT interval (D), and QTc (Mitchell correction) (E) during 30 min of in vivo electrocardiogram (ECG) monitoring after venous injection of vehicle, FGF23 (9 ng/mL total blood volume), or FGF23 + anti-FGFR4 (10.5 µg/mL total blood volume). *P < 0.05 compared with vehicle; n = 9 vehicle, n = 11 FGF23, and n = 8 FGF23 + anti-FGFR4.