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. 2021 Sep 8;20:179. doi: 10.1186/s12933-021-01364-w

Table 5.

Stepwise regression analysis for incident diabetic patients after dialysis with 5-year survival rate, n = 335

Variables Univariate Multivariate
HR (95% CI) P-value aHR (95% CI) P-value
Age > 60 years 2.52 (1.67–3.79)  < 0.001 2.35 (1.56–3.55)  < 0.001
Gender—male 1.40 (0.98–2.00) 0.068
Anti-diabetic drug use
 OHA 1
 Insulin 1.63 (1.14–2.33) 0.008 1.41 (0.98–2.02) 0.068
Region
 Northern 1
 Central 1.23 (0.80–1.89) 0.900
 Southern/Eastern 0.94 (0.63–1.52) 0.398
Insured premium (NT$)
 < 15,840 1
 15,840–25,000 0.78 (0.51–1.20) 0.254
 > 25,000 0.87 (0.55–1.38) 0.543
Urbanization
 Urban 1
 Sub-urban 0.75 (0.50–1.12) 0.157
 Rural 0.84 (0.47–1.62) 0.565
Hospital characteristics
 Medical center 1.19 (0.81–1.76) 0.378
 Region/others 1
Number of admissions during the 12 months leading up to dialysis
 0–1 1
 > 1 1.59 (1.05–2.43) 0.031
Dialysis modality
 Peritoneal dialysis 1
 Hemodialysis 1.24 (0.54–2.81) 0.614
Comorbidity
 Hypertension 1.22 (0.85–1.75) 0.275
 Hyperlipidemia 0.43 (0.23–0.81) 0.008 0.45 (0.24–0.85) 0.014
 Gout 0.85 (0.50–1.46) 0.557
 Congestive heart failure 1.27 (0.85–1.89) 0.239
 Cerebrovascular accident 2.03 (1.28–3.22) 0.003 2.04 (1.27–3.29) 0.003
 COPD 1.92 (1.18–3.14) 0.009 1.68 (1.03–2.76) 0.039
 Chronic liver disease 1.00 (0.47–2.15) 0.998
 Malignancy 1.65 (0.98–2.80) 0.061
ACEI/ARB use 0.68 (0.48–0.97) 0.033
Lipid-lowering drugs use 0.50 (0.33–0.76) 0.001 0.66 (0.43–1.02) 0.060

HR hazard ratio, CI confidence interval, aHR adjusted hazard ratio, OHA oral hypoglycemia agents, COPD chronic obstructive pulmonary disease, ACEI angiotensin converting enzyme inhibitors, ARB angiotensin II receptor blockers