Fig. 2.

Distribution of crude and age-standardized explicitly defined sepsis (R65.1 – severe sepsis, R57.2 septic shock according to the 1992 sepsis-1 definitions [18]) incidence across German districts. Maps were created using the ‘spplot’ function from the ‘sp’ package [31, 32]. Geodata and shapefiles for creating maps of Germany in R were retrieved from https://gadm.org/. The maps are freely available for academic use