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. 2021 Sep 7;21:1001. doi: 10.1186/s12885-021-08699-3

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© The Author(s) 2021

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 9 — The expression and prognostic value of COMMD3 was validated in GSE14520 and HCC patients. A COMMD3 expression in GSE14520 datasets between one thirds of the highest expression and two thirds of the lowest expression. B K-M OS curves in GSE14520 datasets stratified by COMMD3 expression. C COMMD3 expression in normal and tumor tissue of 80 HCC patients. D K–M OS curves in 80 HCC patients stratified by COMMD3 expression. E CCK-8 cell proliferation assay results in Hep3B and HepG2 cells transfected with si-COMMD3, or negative control (NC). F EdU cell proliferation assay results in Hep3B and HepG2 cells transfected with si-COMMD3, or NC. * p < 0.05, *** p < 0.001