Fig. 6.

Time-dependent internalization and exclusion of FLPS particles. The phase-contrast, fluorescence, and superimposed images of HaCaT cells exposed to 500 µg/mL concentration of 200 nm sized FLPS particles. For fluorescent imaging, DAPI (λ_ex: 357/44 nm; λ_em: 447/60 nm) and GFP (λ_ex: 470/22 nm; λ_em: 510/42 nm) fluorescent light cubes were used. Image arrangements from top to bottom: control, 24, 48, 72, 96 and 120 h, respectively. Scale bar: 20 μm