TABLE 3.

Incidence Rates of CHD by Type of Health Care Encounters and Associations Between CHD and Baseline LDL Cholesterol

Health Care Settings		Baseline LDL Cholesterol (mg/dL)
	< 70	70–99	100–129	130–159	160–189	≥ 190
CHD cases diagnosed in all health care settings
No. patients	12,127	24,745	18,413	7059	1881	630
No. cases	3057	4908	2781	897	276	96
Person-years	23,886	63,094	50,239	18,187	4495	1425
Incidence rate	127.98	77.79	55.36	49.32	61.40	67.37
Age-adjusted HR (95% CI)	1.93 (1.83–2.03)	1.28 (1.22–1.34)	1.00	0.94 (0.87–1.01)	1.17 (1.03–1.32)	1.37 (1.12–1.68)
Multivariable-adjusted HR (95% CI)	1.30 (1.20–1.41)	1.07 (1.01–1.13)	1.00	1.09 (1.00–1.18)	1.41 (1.23–1.63)	1.74 (1.37–2.21)
CHD cases diagnosed only in inpatient and emergency encounters
No. patients	10,050	21,360	16,577	6473	1702	582
No. cases	980	1523	945	311	97	48
Person-years	21,604	58,571	47,422	17,303	4254	1349
Incidence rate	45.36	26.00	19.93	17.97	22.80	35.58
Age-adjusted HR (95% CI)	1.93 (1.77–2.11)	1.20 (1.10–1.30)	1.00	0.96 (0.84–1.09)	1.24 (1.01–1.53)	2.05 (1.54–2.74)
Multivariable-adjusted HR (95% CI)	1.17 (1.01–1.36)	0.99 (0.90–1.10)	1.00	1.15 (0.99–1.32)	1.61 (1.26–2.05)	2.70 (1.88–3.87)
Difference in age-adjusted HR (95% CI)	1.00 (0.90–1.11)	0.93 (0.85–1.03)	—	1.02 (0.88–1.18)	1.06 (0.83–1.35)	1.50 (1.05–2.13)*
Difference in multivariable-adjusted HR (95% CI)	0.90 (0.76–1.07)	0.93 (0.83–1.04)	—	1.05 (0.89–1.24)	1.14 (0.86–1.50)	1.55 (1.01–2.39)*

The unit of incidence rate is the number of new cases per 1000 person-years.

^*P < 0.05.

CHD indicates coronary heart disease; CI, confidence interval; HR, hazard ratio; LDL, low-density lipoprotein.