Table 2.
Coagulation function indexs of proband and family members in hereditary protein S deficiency family
| Items | Propositus (III5) | Father (II7) |
Mother (II8) |
Brother (III6) |
Member (II1) |
Member (II6) | Member (II10) | reference value |
|---|---|---|---|---|---|---|---|---|
| PT (s) | 13.3 | 11.2 | 11.8 | 12.3 | 9.8 | 11.9 | 12.1 | 9.9–12.9 |
| APTT (s) | 27.9 | 26.4 | 28.8 | 32 | 27.1 | 24.3 | 23.9 | 23.3–32.5 |
| TT (s) | 15.5 | 15.8 | 17.0 | 30.9 | 17.1 | 16.4 | 19.2 | 14–21 |
| Fg (g/L) | 2.57 | 2.32 | 2.7 | 1.9 | 2.41 | 2.79 | 2.34 | 1.8–3.5 |
| D-dimer | 25.8 | 0.24 | 13.2 | 15.5 | 0.23 | 0.01 | 0.01 | 0–0.55 |
| TPS (mg/L) | 67 | 208 | 85 | 71 | – | – | – | 160–260 |
| FPS (mg/L) | 19 | 66 | 22 | 23 | – | – | – | 48–67 |
| PS(%) | < 16 | 84.4 | < 16 | 16.7 | 102.7 | 97.4 | 112.3 | Male:75–130 Female:52–118 |
| PC(%) | 66.9 | 90.1 | 100.2 | 60.2 | 113.4 | 124.2 | 98.1 | 70–140 |
| AT-III(%) | 92 | 107.6 | 97.4 | 85.9 | 121.2 | 109.1 | 97.1 | 75–125 |
Note: PT prothrombin time; INR international normalized ratio; APTT activated partial thromboplastin time; TT thrombin time; Fg fibrinogen; FDP fibrin degradation products; TPS total protein S; FPS free protein S; PS protein S; PC protein C; AT antithrombin III