Fig. 5.

Lung cytokine gene expression profile. Cytokine expression in response to MWCNT was largely unaltered by lung MMP blockade. a Il1b gene expression. b Il6 gene expression. c Ccl2 gene expression. d Tgfb gene expression. e Tnfa gene expression. f Icam1 gene expression. g Vcam1 gene expression. Marimistat only inhibited Tnfa expression (e). p values based on 2-way ANOVA presented for each figure. N = 4–5 per group. Data presented are means ± SEM