Table 2.
The relationship between positive expression of NNMT in tumor stroma and clinical pathological characteristics in 177 patients with CRC.
| Characteristics | n | Stroma | ||
|---|---|---|---|---|
| NNMTH (%) | Pearsonχ2 | P value | ||
| Total | 177 | 89(50.3) | ||
| Gender | 0.003 | 0.985 | ||
| Male | 119 | 60(50.4) | ||
| Female | 58 | 29(50.0) | ||
| Age | 0.051 | 0.821 | ||
| <61 | 88 | 45(51.1) | ||
| >=61 | 89 | 44(49.4) | ||
| TNM | 4.961 | 0.026* | ||
| Ⅰ-Ⅱ | 104 | 45(43.3) | ||
| Ⅲ-Ⅳ | 73 | 44(60.3) | ||
| T | 1.287 | 0.257 | ||
| T1+T2 | 21 | 13(61.9) | ||
| T3+T4 | 156 | 76(48.7) | ||
| Lymph node metastasis | 4.374 | 0.036* | ||
| N0 | 107 | 47(43.9) | ||
| N1-2 | 70 | 42(60.0) | ||
| Distance metastasis | 3.858 | 0.050* | ||
| M0 | 159 | 76(47.8) | ||
| M1 | 18 | 13(72.2) | ||
| Histology | 4.557 | 0.207 | ||
| Mucinous adenocarcinoma | 23 | 9(39.1) | ||
| Non-Mucinous adenocarcinoma | 148 | 79(53.4) | ||
| Squamous cell carcinoma | 5 | 1(20.0) | ||
| Signet-ring cell carcinoma | 1 | 0(0.0) |
NNMTH: NNMT high expression