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Vildagliptin inhibit miR-134-5p in aorta to activate Bdnf to moderate endothelial function; activate miR-190a-5p to inhibit Ccl2; and inhibit miR-375-3p to activate Pdk1 to inhibit apoptosis.
Bdnf – brain-derived neurotrophic factor, Ccl2 – C-C motif chemokine ligand 2, Pdk1 – 3-phosphoinositide dependent protein kinase-1.
