Table II.
Characteristics of early toxicity (WHO classification) in studied group of patients along with the division into HPV+ and HPV–
| Toxicity | Entire group n (%) | HPV+ n (%) | HPV– n (%) | P-value |
|---|---|---|---|---|
| Red blood cells: | ||||
| Grade 0 | 84 (86) | 44 (88) | 40 (83) | 0.3890 |
| Grade 1 | 13 (13) | 5 (10) | 8 (17) | |
| Grade 2 | 0 | 0 | 0 | |
| Grade 3 | 1 (1) | 1 (2) | 0 | |
| White blood cells: | ||||
| Grade 0 | 67 (69) | 33 (66) | 34 (71) | 0.9023 |
| Grade 1 | 16 (16) | 8 (16) | 8 (17) | |
| Grade 2 | 10 (10) | 6 (12) | 4 (8) | |
| Grade 3 | 5 (5) | 3 (6) | 2 (4) | |
| Platelets: | ||||
| Grade 0 | 90 (92) | 46 (92) | 44 (92) | 0.3611 |
| Grade 1 | 5 (5) | 3 (6) | 2 (4) | |
| Grade 2 | 2 (2) | 0 | 2 (4) | |
| Grade 3 | 1 (1) | 1 (2) | 0 | |
| Mucositis: | ||||
| Grade 0 | 2 (2) | 1 (2) | 1 (2) | 0.8514 |
| Grade 1 | 14 (14) | 7 (14) | 7 (15) | |
| Grade 2 | 71 (73) | 36 (70) | 37 (75) | |
| Grade 3 | 11 (11) | 7 (14) | 4 (8) | |
| Skin reaction: | ||||
| Grade 0 | 2 (2) | 1 (2) | 1 (2) | 0.9167 |
| Grade 1 | 34 (35) | 19 (38) | 15 (31) | |
| Grade 2 | 50 (51) | 24 (48) | 26 (54) | |
| Grade 3 | 12 (12) | 6 (12) | 6 (13) | |