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Inhibition of excitatory neurons in the anterior cingulate cortex (ACC) relieves hyperalgesia in the CCI mouse model. A, B – show the mechanical and thermal pain threshold test results of CCI mice when stimulated with blue light in the ACC (n = 8 or 10, p > 0.05). C, D – show the mechanical pain threshold test and thermal pain threshold test results of CCI mice when the ACC was inhibited by yellow light (n = 9 or 10, *p < 0.05, ***p < 0.001)
