Table I.
Nonconformity with EULAR recommendations in clinical practice in Poland
EULAR recommendations for RA patients | Declarative estimates as stated by rheumatologists | |
---|---|---|
Inconsistency in applying recommendations in practice | Mean % patients | |
Therapy with csDMARDs should be started as soon as the diagnosis of RA is made | Treatment not initiated at diagnosis | 15 |
Lag time in treatment initiation from diagnosis (> 3 months) | 29 | |
Treatment should be aimed at reaching a target of sustained remission or low disease activity in every patient | Never achieving remission | 64 |
Time to first-ever remission (> 6 months) | 54 | |
Sustained remission (> 12 months) | 19 | |
Monitoring should be frequent in active disease (every 1–3 months); if there is no improvement by at most 3 months after the start of treatment or the target has not been reached by 6 months, therapy should be adjusted | Interval of disease activity monitoring (> 3 months) | 33 |
MTX should be part of the first treatment strategy | Lack of MTX use in monotherapy or in combination with GC and/or other csDMARDs | 10–12 |
Short-term glucocorticoids should be considered when initiating or changing csDMARDs, in different dose regimens and routes of administration, but should be tapered as rapidly as clinically feasible | GC treatment time (> 6 months) | 25 |
If the treatment target is not achieved with the first csDMARD strategy, when poor prognostic factors are present, addition of a bDMARD or a tsDMARD should be considered; current practice would be to start a bDMARD | No bDMARD treatment planned (despite active disease after ≥ 2 treatment schemes/drugs) | 34 |
Referred for bDMARD treatment (active disease only after ≥ 3 treatment schemes/drugs) | 51 |