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. 2021 Sep 8;2021(9):CD009437. doi: 10.1002/14651858.CD009437.pub3

4. Table of study characteristics outcomes: functional and maximum exercise capacity.

Author Outcome domain Outcome measure Time points in months (time frame) Data presented Pooled
Bendstrup 1997 functional exercise capacity 6MWD 1 (ST); 3 (ST); 6 (ST) mean change, SEM, group/P value Yes
Bernocchi 2017 functional exercise capacity 6MWD 4 (ST); mean change, 95% CI, N/group Yes
Bourbeau 2003 functional exercise capacity 6MWD 4 (ST); 12 (MT) not reported No
Boxall 2005 functional exercise capacity 6MWD 3 (ST) mean, mean change, SD mean/group, P value Yes
Cambach 1997 functional and maximum exercise capacity 6MWD, W‐max 3 (ST); 6 (ST) mean change, SD, N/group Yes
Engstrom 1999 functional exercise capacity 6MWD 12 (MT) mean, SE, N/group/time point Yes
Fernandez 2009 functional exercise capacity 6MWD, leg fatigue score 12 (MT) mean, SD, N/group/time point Yes
Gottlieb 2011 functional and maximum exercise capacity 6MWD 6 (ST); 12 (MT); 18 (LT) mean, SD, N/group/time point Yes
Güell 2000 functional and maximum exercise capacity 6MWD, W‐max 3 (ST); 6 (ST); 9 (MT); 12 (MT); 18 (LT); 24 (LT) mean, SE, group/time point Yes
Güell 2006 functional exercise capacity 6MWD 4 (ST) mean, SD, N/group/time point Yes
Jimenez‐Reguera 2020 functional exercise capacity 6MWD 6 (ST); 12 (MT) mean, SD, N/group/time point Yes
Kalter‐Leibovici 2018 functional exercise capacity 6MWD 12 (MT); 24 (LT) mean change, SD, N/group Yes
Kessler 2018 functional exercise capacity 6MWD 12 (MT) mean, SD, N/group (at 12 months) 
adjusted MD, 95% CI, N, P value Yes
Khan 2019 functional exercise capacity 6MWD 6 (ST) mean change, SD, N/group, MD, 95% CI Yes
Ko 2016 functional exercise capacity 6MWD 12 (MT) mean change, SD, N/group, P value Yes
Littlejohns 1991 functional exercise capacity 6MWD 12 (MT) mean change, 95% CI, N/group Yes
Lou 2015 functional exercise capacity 6MWD 48 (LT) mean change, SD, N/group
adjusted median D, 95% CI, P value Yes
Mendes 2010 functional exercise capacity 6MWD 3 (ST) mean, SD, N/group/time point ‐ box and whisker plots Yes
Rea 2004 functional and maximum exercise capacity Shuttle walk test 12 (MT) mean, N/group/time point, P value difference No
Strijbos 1996 functional and maximum exercise capacity W‐max, 4MWT, Borg scores during cycle test 6 (ST); 12 (MT); 18 (LT) mean, SD, N/group/time point Yes
Tabak 2014 functional exercise capacity 6MWD 1 (ST); 3 (MT) mean, SD, N/group/time point Yes
Theander 2009 functional and maximum exercise capacity 6MWD, grip strength 3 (ST) mean change, SD, N/group Yes
van Wetering 2010 functional and maximum exercise capacity 6MWD, W‐max 4 (ST); 12 (MT); 24 (LT) mean change, SE, N/group Yes
Vasilopoulou 2017 functional and maximum exercise capacity 6MWD, W‐max 2 (ST); 14 (MT) mean, SD, N/group/time point Yes
Wakabayashi 2011 functional exercise capacity 6MWD 6 (ST); 12 (MT) mean change, SD, N/group/time point, P value Yes
Wang 2017 functional exercise capacity 6MWD 1 (ST); 3 (ST); 6 (ST); 12 (MT) mean change, SD, N/group Yes
Zhang 2020 functional exercise capacity 6MWD 3 (ST); 6 (ST); 12 (MT); 24 (LT) mean, SD, N/group/time point Yes
Wijkstra 1994 functional exercise capacity 6MWD 3 (ST); 6 (ST); 12 (MT); 18 (LT) mean change, SD, N/group Yes (3 months only)

Abbreviations. 4MWT: 4‐minute walk test; 6MWD: 6‐minute walking distance; CI: confidence interval; LT: long‐term follow‐up; 
MD: mean difference; MT: medium‐term follow‐up; SD: standard deviation; SE: standard error; ST: short‐term follow‐up; W‐max: maximum exercise capacity (in watts).