Steed 2017.

Study name	TANDEM study ‐ Tailored intervention for ANxiety and DEpression Management in COPD
Methods	RCT with 6 and 12 months' follow‐up to investigate whether a cognitive‐behavioural approach (CBA) intervention, delivered prior to PR, can help to improve mild to moderate anxiety and/or depression in those with moderate to very severe COPD and consequently encourage PR uptake/completion (phase III of the TANDEM study)
Participants	Adults living with COPD recruited from primary care, community clinics, or secondary care clinics, or following referral to PR services, who have symptoms of mild to moderate comorbid anxiety or depression on screening; caregivers of patients
Interventions	A tailored, psychological intervention for mild to moderate anxiety and/or depression in people with chronic obstructive pulmonary disease (COPD)
Outcomes	Anxiety, depression (primary outcomes), dyspnoea, health‐related quality of life, functional activity, smoking status, process outcomes, cost‐effectiveness outcomes
Starting date	April 2016
Contact information	s.j.c.taylor@qmul.ac.uk
Notes

6MWD: six‐minute walking distance.
AECOPD : acute exacerbation of COPD .
ADL: activities of daily living.
BMI: body mass index.
BODE: BMI, airflow Obstruction, Dyspnoea, and Exercise Capacity.
CAT: COPD Assessment Test .
CCQ: COPD Control Questionnaire .
COPD: chronic obstructive pulmonary disease.
DM: diabetes mellitus .
ED: emergency department .
EQ‐5D: EuroQol Quality of Life ‐ 5 domain s.
FEV₁: forced expiratory volume in one second .
FVC: forced vital capacity .
GOLD: Global Initiative for Chronic Obstructive Lung Disease.
HADS: Hospital Anxiety and Depression S cale .
HF: heart failure .
IDM: integrated disease management.
m MRC: modified Medical Research Council D yspnoea Scale .
PAM: patient activation measure.
RCT: randomised controlled trial.
VAS: visual analogue scale .