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. 2021 Feb 26;22(5):bbab006. doi: 10.1093/bib/bbab006

Table 5.

Validation of gene prioritization results by MEGASTROKE GWAS

SNP Gene Sig. genes in GWAS
Algorithm (Sig./total) (Sig./total) Median rank Hits@10% Hits list
RWR 411/3110 25/200 5251 2/7 ICA1L, SEMA4A
N2V 1139/3027 53/200 4526 1/7 SEMA4A
DIAMOnD 47/2649 3/200 na 0/7
GenePanda 1859/2918 90/200 8544 1/7 ZCCHC14
RWRH 784/2767 45/200 1840 4/7 SH3PXD2A, SEMA4A, ICA1L, ZCCHC14
N2VH 1597/2590 70/200 5979 1/7 SH3PXD2A
IDLP 603/3700 41/200 9318.5 1/7 ZCCHC14
Degree centrality 385/2144 31/200 7697 0/7