Table 3 ‒
Summary of treatment-emergent adverse events (TEAEs) in patients with hyperphosphatemia versus non-hyperphosphatemia
| Parameter, n (%) | Hyperphosphatemia (n = 48) | Non-hyperphosphatemia (n = 19) |
|---|---|---|
| Any TEAE | 48 (100.0) | 18 (94.7) |
| Grade 3 or 4 TEAE | 34 (70.8) | 12 (63.2) |
| Serious TEAE | 17 (35.4) | 7 (36.8) |
| Treatment-related TEAE | 47 (97.9) | 17 (89.5) |
| Serious treatment-related TEAE | 3 (6.3) | 1 (5.3) |
| TEAE leading to treatment discontinuation | 3 (6.3) | 7 (36.8) |
| TEAE leading to dose interruption/dose adjustment | 43 (89.6) | 10 (52.6) |
Hyperphosphatemia and non-hyperphosphatemia were defined as serum phosphorus levels >5.5 and ≤5.5 mg/dl after the dose, respectively.